While pancreas transplantation offers significant benefits for eligible candidates, it is not without risks and potential complications. The surgery itself carries the usual risks associated with major abdominal procedures, such as bleeding, infection, and complications related to anesthesia. Additionally, because pancreas transplantation requires lifelong immunosuppressive medication to prevent rejection of the donor organ, recipients are at increased risk of infections and other side effects associated with immunosuppression. Therefore, careful patient selection, thorough evaluation, and comprehensive postoperative care are essential to optimize outcomes and minimize risks for individuals undergoing pancreas transplantation
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